Bronchial Asthma | Causes and Treatment of Asthma

Asthmatic Reaction: Causes and Proven Clinical Treatment

Bronchial asthma (definition) is a chronic health disorder that involves:
- Bronchoconstriciton or bronchospasm (narrowing of airways)
- Inflammation of airways
- Increased sensitivity of the immune system to triggers (dust mites, pollen, smoke, etc.)
- Excessive production of mucus in airways.

Cause of asthmatic reaction

People with bronchial asthma are chronic hyperventilators.

Breathing rates (minute ventilation) of people with asthmatic reaction at rest

Table. Minute ventilation (asthma)

Condition Minute
ventilation
Number of
people
All references or
click below for abstracts
Normal breathing 6 L/min - Medical textbooks
Healthy Subjects 6-7 L/min >400 Results of 14 studies
Asthma 13 (~+mn~2) L/min 16 Chalupa et al, 2004
Asthma 15 L/min 8 Johnson et al, 1995
Asthma 14 (~+mn~6) L/min 39 Bowler et al, 1998
Asthma 13 (~+mn~4) L/min 17 Kassabian et al, 1982
Asthma 12 L/min 101 McFadden & Lyons, 1968

Note that advanced stages of asthma can lead to lung destruction, ventilation-perfusion mismatch,
and arterial hypercapnia causing further reduction in body oxygen levels.

Chronic hyperventilation causes reduced CO2 levels in alveoli and airways of the lungs.

Low CO2 causes spasm of airways

Since CO2 is a powerful relaxant of smooth muscles, alveolar hypocapnia also causes spasm of airways or bronchoconstriction (Sterling, 1968). Dr. Herxheimer was the first clinical physician who suggested that hypocapnia or low CO2 was the cause of asthma (Herxheimer, 1946 and 1952) in his articles "Hyperventilation asthma" and "The late bronchial reaction in induced asthma".

Brain O2 levels: changes after overbreathing Low CO2 causes cell hypoxia and allergies

Since CO2 is a potent vasodilator, reduced CO2 levels in the blood causes cell hypoxia leading to the suppressed and distorted reactions of the immune system. This creates the foundation for appearance of allergies and inflammation in airways with production of excessive mucus. Additional damage often takes place due to incorrect exercise leading to sports induced asthma.

With prolonged hyperventilation and inflammation, some people develop severe asthma due to destruction of their lungs and ventilation-perfursion mismatch. This further reduces body oxygenation and makes symptoms of asthma worse.

Treatment of asthmatic reaction

These and other down-to-Earth factors are presented in these YouTube videos "Asthma Causes and Treatment" and "Asthma Treatment".

Coughing and acute asthma web pages:
- Stop bronchial asthma exacerbation in 2-3 min with a breathing exercise
- Stop coughing at night - A breathing exercise to reduce duration and severity of coughing at night. This exercise also helps to fall asleep faster.

Further resources:
- Asthma treatment
- Clinical effects of the Buteyko breathing technique on asthma in bronchi.

References

Sterling GM, The mechanism of bronchoconstriction due to hypocapnia in man, Clinical Science 1968 Apr; 34(2): p. 277-285.

Herxheimer H, Hyperventilation asthma, Lancet 1946, 6385: p. 83-87.

Herxheimer H, The late bronchial reaction in induced bronchial asthma, Internal Archives of Allergy and Applied Immunology 1952; 3: p. 323-328.

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