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What Causes Seizures? Low Brain CO2 and O2

Brain: Epilepsy SeizuresWhat is the cause of seizures on a cell level? During a seizure there is a spontaneous temporary intensification of electrical signals or electrical disturbances that result in abnormal behavior (e.g., convulsions, repetitive automatic movements of body parts, tremors, or muscle spasms), strange emotions, or even loss of consciousness. An epileptic seizure is a medical condition or a brain disorder that takes place when clusters of neurons in the electrical system of the brain generate abnormally high numbers of spontaneous and asynchronous electrical discharges. The threshold of excitability or the seizure threshold becomes too low.

Note that there are numerous environmental and lifestyle factors, including stress, overeating, infection, fever, high and low blood sugar (hyperglycemia and hypoglycemia), marijuana and alcohol withdrawal, as well as genetic factors that predetermine individual variations in relation to susceptibility of certain people to these secondary causes of epilepsy and seizures. However, due to several pathological effects, changes in cerebral CO2 and O2 remain the key factors in the cause of epilepsy and seizures.

Key causes of seizures

Brain hypervenitlation effectsArterial hypocapnia (a low CO2 level in the arterial blood) is typical in modern people (see links below) and is even more pronounced in the sick. It is the main cause of seizures. Among other factors, the main effects of hypocapnia caused by hyperventilation in relation to the seizures cause are:
- increased excitability of nerve cells that lowers seizure threshold
- reduced brain-oxygen level and increased cellular acidity (low pH in cells)
- reduced glucose availability for the brain
- worsened blood-glucose control
- increased muscular tension
- worsened ability to resist stress due to a weakened immune system.

Mouth breathing (due to CO2 losses and a lack of absorption of nitric oxide generated in the sinuses) and chest breathing (in opposition to diaphragmatic breathing) are additional factors that worsen blood gases in the brain (reduced O2 and CO2 levels), reduce body-oxygen levels, reduce perfusion (blood supply) of the brain and can cause seizures or make them worse.

Do medical studies prove that CO2 can cause seizures to disappear?

Who were among the first doctors who probably knew the cause of epilepsy? The first medical study that proved the beneficial effects of CO2-enriched air (with "The effect of epileptic seizures of varying the composition of the respired air") was published over 80 years ago by the Journal of Clinical Investigations (Lennox, 1929). The result was replicated in the 1956 article published in Science, as is clearly indicated in the title “Inhibition of audiogenic seizures by carbon dioxide” (Mitchell and Grubbs, 1956). In both studies, inhalation of CO2-rich air reduced duration and severity of seizures due to the known effects of carbon dioxide on nerve and muscle cells. More recently, in 2006, Finnish scientists, after studying febrile seizures in rat pups, stated that “Suppressing alkalosis with 5% ambient CO2 abolished seizures within 20 s” (Schuchmann et al, 2006).

Causes of seizures are devastating for health-related effects worldwide these days

The condition affects about 1% of people in the western world. Most seizures are not life-threatening. However, prolonged seizures (lasting more than 5 minutes) are very dangerous and can cause death due to epilepsy. They are called “status epilepticus” and affect over half a million westerners. While some people believe that status epilepticus happen mostly in those people who have a previous history of seizures (or in former epileptics), up to 50-60% of people who experience status epilepticus have never had seizures in their past and did not have a diagnoses of epilepsy. The death toll due to status epilepticus is over 100,000 western people each year. Many people in status epilepticus experience prolonged or repeated non-convulsive seizures, while others have severe convulsive seizures. Both states should be treated as dangerous. Brain damage often occurs as a result of seizures.

All these research articles clearly demonstrated that CO2 is an effective treatment to prevent epilepsy and stop seizures. Hence, if an epileptic normalizes their arterial CO2 and eliminates the cause of seizures by learning how to breathe no more than the international norm for breathing, the symptoms of epilepsy will completely disappear.

Studies related to causes of a seizure

Medical professionalsIn 1984 the American Journal of Medicine published a case report about a 66-year-old man who had a history of absence spells for more than 20 years. After educational and behavioral therapy targeted to eliminate chronic hyperventilation, the patient had a long and continuous remission of his spells (Magarian and Olney, 1984).

Another breathing retraining attempt is described in the article "Behavioral control of intractable idiopathic seizures: I. Self-regulation of end-tidal carbon dioxide" published in Psychosomatic Medicine (Fried et al, 1984). This time 18 patients were able to partially normalize their breathing pattern and significantly reduced both the severity and frequency of seizures (see the abstract below).

American doctors from the Boston Neurobehavioral Institute (Harvard Medical School) applied the same approach (elimination of hyperventilation) for two children with severe developmental problems. Their parents, teachers and caretakers were taught to modify the children's breathing so that they could stop and prevent seizures (Bruno-Golden & Holmes, 1993).

Sick people and their doctorsWhile deliberate hyperventilation induces seizures, breathing training, as these medical studies testify, produces the opposite effect. This indicates that there is a single cause of seizures that can be triggered by numerous secondary factors. Hyperventilation is the cause of epilepsy.


Arterial hypocapnia (or low CO2) and brain hypoxia due to hyperventilation (i.e. overbreathing) are the key causes of seizures. A Lack of sree electrons from the Earth (i.e., the positive body charge) play an additional role as a cause of seizures.

Based on these findings, our next step is to find the optimum way How to Stop Seizures Naturally (a simple breathing exercise), when it's possible (sometimes the onset can be too sudden). Then we can create a treatment program to prevent seizures using breathing normalization. Such program of treatment was suggested and tested by Russian doctors on hundreds of people with epilepsy and seizures. More than 30 seconds for the body-oxygen test 24/7 is the general requirement for disappearance of seizures.

There is one more natural factor X and cause that often provides an immediate relief in relation to duration and intensity of seizures. Some people clai that they managed to eliminate all seizures completely with this factor X. Factor X is so natural that it had been common for nearly all evolution of mankind, but over 99% of modern people are lacking factor X. You can find the name of this factor right below here as your bonus content.

Tweet or Share this page to reveal the bonus content.

Treatment of seizures with CO2 and breathing techniques is analyzed on these pages:
* Western studies that applied CO2 and Breathing for Treatment of Seizures
* Seizure Threshold Controlled by Breathing Pattern and Blood Gases
* Treatment of Seizures: Program with over 90% success rate since it is based on knowledge of causes of seizures.


Lennox WG, The effect of epileptic seizures of varying the composition of the respired air, J Clin Invest. 1929; 4: 23–24.

Mitchell WG & Grubbs RC, Inhibition of audiogenic seizures by carbon dioxide, Science, 1956; 123: 223–224.

Schuchmann S, Schmitz D, Rivera C, Vanhatalo S, Salmen B, Mackie K, Sipil ST, Voipio J, Kaila K. Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis. Nat Med. 2006; 12: p.817–823.

Esquivel E, Chaussain M, Plouin P, Ponsot G, Arthuis M, Physical exercise and voluntary hyperventilation in childhood absence epilepsy, Electroencephalogr Clin Neurophysiol 1991 Aug; 79(2): p. 127-132.

Wirrel CW, Camfield PR, Gordon KE, Camfield CS, Dooley JM, and Hanna BD, Will a critical level of hypocapnia always induce an absence seizure? Epilepsia 1996; 37(5): p. 459-462.

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