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Bronchospasm: Definition, Symptoms, Causes, and Treatment

Mechanism of BronchospasmBronchospasm (definition) is defined as constriction of bronchi and bronchioles. It can generally happen due to 3 factors:
- a spasm in the smooth muscles of bronchi and bronchioles
- an inflammation of the airways
- excessive production of sputum (mucus) due to an allergic reaction or possible irritation caused by mechanical friction of air (due to shear stress), overcooling or drying of airways (i.e., during exercise induced asthma).

Bronchospasm is a normal physiological reaction to alveolar hyperventilation (Badier et al, 1998; Clarke et al, 1982; Jamison et al, 1987; O'Cain et al, 1979; Sterling, 1968), as you can see from the titles of these articles (see below). Do people with bronchitis, asthma, and other conditions suffer from alveolar hypocapnia (CO2 deficiency in airways)? What is known about minute ventilation in people with bronchospasm?

Ventilation rates (chronic diseases)

Condition Minute
Number of
All references or
click below for abstracts
Normal breathing 6 L/min - Medical textbooks
Healthy Subjects 6-7 L/min >400 Results of 14 studies
Asthma 13 (+-2) L/min 16 Chalupa et al, 2004
Asthma 15 L/min 8 Johnson et al, 1995
Asthma 14 (+-6) L/min 39 Bowler et al, 1998
Asthma 13 (+-4) L/min 17 Kassabian et al, 1982
Asthma 12 L/min 101 McFadden, Lyons, 1968
COPD 14 (+-2) L/min 12 Palange et al, 2001
COPD 12 (+-2) L/min 10 Sinderby et al, 2001
COPD 14 L/min 3 Stulbarg et al, 2001
Cystic fibrosis 15 L/min 15 Fauroux et al, 2006
Cystic fibrosis 10 L/min 11 Browning et al, 1990
Cystic fibrosis* 10 L/min 10 Ward et al, 1999
CF and diabetes* 10 L/min 7 Ward et al, 1999
Cystic fibrosis 16 L/min 7 Dodd et al, 2006
Cystic fibrosis 18 L/min 9 McKone et al, 2005
Cystic fibrosis* 13 (+-2) L/min 10 Bell et al, 1996
Cystic fibrosis 11-14 L/min 6 Tepper et al, 1983

Bronchospasm can be induced by many chemicals that can cause either bronchospasm or bronchodilation, but CO2 plays the key role due to two factors: its vasodilatory potency (see links with medical studies below) and additional negative effects caused by alveolar hypocapnia (lack of CO2), as the Table above proves. 

What else influences bronchospasm?

Chronic hyperventilation (breathing more air than the medical norm) also leads to cell hypoxia and immunosuppression regardless of ventilation-perfusion ratio and arterial CO2 levels (it can get too high for many lung pathologies). As a result of alveolar hyperventilation, there are additional effects, such asMan with coughing causing bronchospasm frequent respiratory infections, excessive production of sputum (mucus) and chronic inflammation. Allergic triggers (dust, pollen, and many others) cause additional problems due to the hypersensitive immune system caused by systemic body hypoxia. All these factors narrow airways and worsen their conductivity, triggering bronchospasm.

Symptoms of Bronchospasm

Bronchospasm symptoms include difficulty breathing, wheezing, coughing, and dyspnea (shortness of breath). Increased respiratory ventilation drastically amplifies the effects of bronchospasm.

Causes and mechanism of Bronchospasm

Bronchospasm mechanism follows from the above Table, which shows that these groups of people are heavy breathers. They all have low CO2 levels in their lungs. As a result of low alveolar CO2, they also have low body-oxygen levels due to effects of alveolar hypocapnia, which either destroys lungs (causing arterial hypercapnia and hypoxemia as for people with COPD) or causes arterial hypocapnia with reduced oxygen transport, as an additional factor that is present during bronchospasm.

Bronchospasm mechanism

Bronchospasm, therefore, due to its effects on oxygen transport, leads to low oxygen levels in tissues and favors chronic inflammation (see links below). As a result, people with lung conditions (asthma, bronchitis, bronchiestasis, bronchiolitis, cystic fibrosis, tuberculosis, sarcoidosis, and many others), experience chronic bronchospasm in the smooth muscles of airways due to chronic alveolar hypocapnia.

This YouTube video explains the cause of bronchospasm.

Surgery of the throat or anesthesia can also be among some rare bronchospasm causes.

Treatment of Bronchospasm

MDs smilingBronchospasm can be successfully treated, as over 180 Russian medical doctors, found. The effective way to deal with Bronchospasm is the Buteyko breathing medical therapy that is approved by the Russian Ministry of Health. It has been applied on more than 200,000 people with health problems (such as asthma, bronchiestasis, bronchiolitis, bronchitis, COPD, and many others) that involve bronchospasm.

Bronchospasm cure (clinical remission), according to these Russian medical doctors, as well as my experience with 100s of my breathing students, has simple criterion and goals for a person to achieve.

Tweet or Share this page to reveal the bonus content.

Physical exercise with nose breathing is a very beneficial lifestyle factor that assists breathing retraining and gradual increase in body oxygen stores. Nose breathing at exercise prevents exercise-induced asthma and bronchospasm.

Bronchospasm symptoms can be effectively eliminated with breathing exercises that involve those breathing devices that trap exhaled CO2 (such as the Amazing DIY breathing device, Frolov breathing device, and Samozdrav). These devices help to increase body-oxygen levels and reduce bronchospasm in a matter of minutes. However, up to 2-4 weeks are often necessary in order to significantly change automatic or basal breathing patterns. Any bronchospasm treatment must also address lifestyle changes (prevention of supine sleep, prevention of mouth breathing, and so forth). The best lifestyle program can be found in the Buteyko technique. Oxygen Remedy online webinars is likely the easiest way to achieve clinical remission in relation to bronchospasm.

* The upper left illustration is by Victor Lunn-Rockliffe

- This page in Spanish: Broncoespasmo: definición, síntomas, causas y tratamiento.

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