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Table 1a. Western scientific evidence about prevalence of CHV
(chronic hyperventilation) in patients with heart disease.

*One row corresponds to one medical study/publication
Condition Minute
ventilation
Number of
patients
Prevalence
of CHV
References (click
below for abstracts)
Normal breathing 6 l/min - 0 % Medical textbooks
Heart disease 15 (±4) l/min 22 100% Dimopoulou et al, 2001
Heart disease 16 (±2) l/min 11 100% Johnson et al, 2000
Heart disease 12 (±3) l/min 132 100% Fanfulla et al, 1998
Heart disease 15 (±4) l/min 55 100% Clark et al, 1997
Heart disease 13 (±4) l/min 15 100% Banning et al, 1995
Heart disease 15 (±4) l/min 88 100% Clark et al, 1995
Heart disease  14 (±2) l/min 30 100% Buller et al, 1990
Heart disease 16 (±6) l/min 20 100% Elborn et al, 1990

References (in the same order)

Dimopoulou et al, 2001 (click on the name to read the abstract of the study)

Dimopoulou I, Tsintzas OK, Alivizatos PA, Tzelepis GE, Pattern of breathing during progressive exercise in chronic heart failure, Int J Cardiol. 2001 Dec; 81(2-3): p. 117-121.

Intensive Care Unit and Pulmonary Function Laboratory, Onassis Cardiac Surgery Center, Athens, Greece.


Johnson et al, 2000

Johnson BD, Beck KC, Olson LJ, O'Malley KA, Allison TG, Squires RW, Gau GT, Ventilatory constraints during exercise in patients with chronic heart failure, Chest 2000 Feb; 117(2): p. 321-332.

Divisions of Cardiovascular, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA.


Fanfulla et al, 1998

Fanfulla F, Mortara , Maestri R, Pinna GD, Bruschi C, Cobelli F, Rampulla C, The development of hyperventilation in patients with chronic heart failure and Cheyne-Stokes respiration, Chest 1998; 114; p. 1083-1090.

Respiratory Function Laboratory, IRCCS, S. Maugeri Foundation, Montescano Medical Center, Pavia, Italy.


Clark et al, 1997

Clark AL, Volterrani M, Swan JW, Coats AJS, The increased ventilatory response to exercise in chronic heart failure: relation to pulmonary pathology, Heart 1997; 77: p.138-146.

Departnent of Cardiac Medicine, National Heart and Lung Institute, London, UK.


Banning et al, 1995

Banning AP, Lewis NP, Northridge DB, Elbom JS, Henderson AH, Perfusion/ventilation mismatch during exercise in chronic heart failure: an investigation of circulatory determinants, Br Heart J 1995; 74: p.27-33.

Department of Cardiology, College of Medicine, University of Wales, Cardiff, UK.


Clark et al, 1995

Clark AL, Chua TP, Coats AJ, Anatomical dead space, ventilatory pattern, and exercise capacity in chronic heart failure, Br Heart J 1995 Oct; 74(4): p. 377-380.

Departnent of Cardiac Medicine, National Heart and Lung Institute, London, UK.


Buller et al, 1990

Buller NP, Poole-Wilson PA, Mechanism of the increased ventilatory response to exercise in patients with chronic heart failure, Heart 1990; 63; p.281-283.

The National Heart and Lung Institute and National Heart Hospital, London, UK.


Elborn et al, 1990

Elborn JS, Riley M, Stanford CF, Nicholls DP, The effects of flosequinan on submaximal exercise in patients with chronic cardiac failure, Br J Clin Pharmacol. 1990 May; 29(5): p.519-524.

Royal Victoria Hospital, Belfast, Northern Ireland.

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