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Diabetes? Only in People with Heavy Breathing

What causes diabetes on a cell level?

Each and every person with diabetes is a heavy breather. This fact was confirmed by all 5 clinical studies that measured minute ventilation in patients with diabetes.

Diabetes: minute ventilation rates

Minute ventilation (or breathing rates) in people with diabetes

*One row corresponds to one research paper or medical science article
Condition Minute
ventilation
Number of
patients
All references or
click below for abstracts
Normal breathing 6 L/min - Medical textbooks
Healthy Subjects 6-7 L/min >400 Results of 14 studies
Diabetes 12-17 L per min 26 Bottini et al, 2003
Diabetes 10-20 L per min 28 Tantucci et al, 1997
Diabetes 13 (±2) L per min 20 Tantucci et al, 1996
Diabetes 15 (±2) L per min 45 Tantucci et al, 2001
Diabetes 12 (±2) L per min 8 Mancini et al, 1999

Brain O2 levels for normal breathing and after hyperventilationAs a result of heavy breathing, people with diabetes should experience reduced blood and O2 delivery to vital organs and extremities of the body. What are the effects of cell hypoxia?

Hypoxia-inducible factor 1 is a protein that signals low levels of oxygen in body cells. This protein regulates the activity of pancreatic cells. As researchers from the Department of Medicine, Stanford University Medical Center (Stanford, California, USA) showed low O2 in cells is the key factor for development of insulin resistance and diabetes (Glassford et al, 2007 - see abstracts below). Many other researchers confirmed this fact (Moritz et al, 2002; Carroll & Ashcroft, 2006; Regazzetti teal, 2009; Halberg teal, 2009; Heinis teal, 2010; Cheng teal, 2010).

Causes of type 2 diabetes: insulin resistance and increased glucose levelsAccording to all these medical studies, tissue hypoxia leads to poor blood glucose and insulin control, and increased insulin resistance.

This is not a big surprise since oxygen is so fundamental for normal cell and organ function. Furthermore, many other chronic diseases (such as cancer, heart disease, and cystic fibrosis), as discussed before, have the same cause. While the cause of diabetes on a cell level is clear, now we can consider the cause of tissue hypoxia in people with diabetes. Why do they have too little oxygen in body cells?

Their heavy breathing leads to excessive CO2 losses (it is called "hypocapnia" or CO2 deficiency in the arterial blood). Hypocapnia leads to a spasm of blood vessels and the reduced Bohr effect. This decreases oxygen delivery and causes elevated levels of hypoxia-inducible factor 1. The presence of chest breathing and mouth breathing are additional factors that worsen oxygen transport to cells and lead to more severe symptoms of diabetes.

The YouTube video "Cause of Diabetes" (on the right side) features Dr. Artour Rakhimov.

Proven medical treatment for diabetes

Medical peopel smilingAccording to the experience of over 150 Russian and Soviet medical doctors, patients with diabetes have less than 20 s for their body-oxygen test results. Furthermore, they develop complications (often life-threatening) when the body-oxygen test result is less than 10 seconds.

On the other hand, during the 2nd conference of Buteyko doctors, Dr. Buteyko and Dr. Samotesova (Chief Endocrinologist of the Krasnoyarsk Region) announced their clinical experience with hundreds of diabetics. The normalization of breathing (about 6 L/min for minute ventilation, over 35 s for the body oxygen test, and less than 70 beats/min for the heart rate at rest) leads to normal blood glucose control in diabetes and no need for insulin use (Buteyko 1991). Note that it is not important what type of diabetes one has: type 1 or type 2. Breathing normalization defeats both types of diabetes. For the effects of the Buteyko method and other breathing retraining methods, visit Symptoms and complications of diabetes.

References
K. P. Buteyko, MD, PhD, The Institute of Clinical Experimental Medicine, Siberian branch of the Academy of Medical Science, USSR, The theory of the pathogenesis of diabetes mellitus. Basic principles of hormone therapy, published in Buteyko method. Its application in medical practice, ed. by K.P. Buteyko, 2nd ed., 1991, Titul, p. 5-9.

References for Diabetes page.

Reference pages: Breathing norms and medical facts:
- Breathing norms: Parameters, graph, and description of the normal breathing pattern
- 6 breathing myths: Myths and superstitions about breathing and body oxygenation (prevalence: over 90%)
- Hyperventilation: Definitions of hyperventilation: their advantages and weak points
- Hyperventilation syndrome: Western scientific evidence about prevalence of chronic hyperventilation in patients with chronic conditions (37 medical studies)
- Normal minute ventilation: Small and slow breathing at rest is enjoyed by healthy subjects (14 studies)
- Hyperventilation prevalence: Present in over 90% of normal people (24 medical studies)
- HV and hypoxia: How and why deep breathing reduces oxygenation of cells and tissues of all vital organs
- Body-oxygen test (CP test) : How to measure your own breathing and body oxygenation (two in one) using a simple DIY test
- Body oxygen in healthy: Results for the body-oxygen test for healthy people (27 medical studies)
- Body oxygen in sick : Results for the body-oxygen test for sick people (14 medical studies)
- Buteyko Table of Health Zones: Clinical description and ranges for breathing zones: from the critically ill (severely sick) up to super healthy people with maximum possible body oxygenation
- Morning hyperventilation: Why people feel worse and critically ill people are most likely to die during early morning hours

References: pages about CO2 effect:
- Vasodilation: CO2 expands arteries and arterioles facilitating perfusion (or blood supply) to all vital organs
- The Bohr effect: How and why oxygen is released by red blood cells in tissues
- Cell oxygen levels: How alveolar CO2 influences oxygen transport
- Oxygen transport: O2 transport is controlled by vasoconstriction-vasodilation and the Bohr effects, both of which rely on CO2
- Free radical generation: Reactive oxygen species are produced within cells due to anaerobic cell respiration caused by cell hypoxia
- Inflammatory response: Chronic inflammation in fueled by the hypoxia-inducible factor 1, while normal breathing reduces and eliminates inflammation
- Nerve stabilization: People remain calm due to calmative or sedative effects of carbon dioxide in neurons or nerve cells
- Muscle relaxation: Relaxation of muscle cells is normal at high CO2, while hypocapnia causes muscular tension, poor posture and, sometimes, aggression and violence
- Bronchodilation: Dilation of airways (bronchi and bronchioles) is caused by carbon dioxide, and their constriction by hypocapnia (low CO2)
- Blood pH: Regulation of blood pH due to breathing and regulation of other bodily fluids
- CO2: lung damage: Elevated carbon dioxide prevents lung injury and promotes healing of lung tissues
- CO2: Topical carbon dioxide can heal skin and tissues
- Synthesis of glutamine in the brain, CO2 fixation, and other chemical reactions
- Deep breathing myth: Ignorant and naive people promote the idea that deep breathing and breathing more air at rest is beneficial for health
- Breathing control: How is our breathing regulated? Why hypocapnia makes breathing uneven, irregular and erratic.

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